BIOL - Biology

BIOL 100 Studying for Success-Biology

The 1-credit course is designed to provide science students with time-management and study skills as they make the transition to the college level learning environment. Properly implemented, the methods will provide freshmen with the opportunity to succeed and potentially excel in college science courses. Many of the skills will likely be applicable to other courses. The strategies introduced include: time-management, daily and weekly study plans, methods of reading text, how to effectively study for a test, and test taking strategies. Students will also be introduced to some to the basic concepts in biology.

1

BIOL 105 Freshman Seminar on Sexual Concerns

Introductory course intended exclusively for freshmen of all majors. The course will include an overview of basic biological concepts related to human sexuality. Major topics of presentation will include information about the male and female reproductive systems, microbiology, immunology, pregnancy, sexually transmitted diseases, and a variety of approaches to protect against disease and unwanted pregnancy.

1

BIOL 109 Biology, Health, and Medicine

The course will provide an introduction to biology as the cellular level with an emphasis on human biology. Students will learn the molecular basis of vaccines and pharmaceutical drugs. To understand vaccines and drugs, students will first learn basic principles of cell biology, biochemistry, genetics, microbiology, and immunology. The course will also incorporate discussions on ethical issues relating to medicine.

3

BIOL 110 Human Biology

Overview of biological aspects of human nature. Survey of basic human physiology, reproduction, and development. Introduction to genetics and the record of human evolution provides starting point for discussion of adaptive significance of human intelligence and social organization.

3

BIOL 111 Introduction to Biology

Introductory course for non-science majors only. Intended to develop an understanding of the operation of biological systems and an acquaintance with basic biological concepts and principles.

3

BIOL 115 Environmental Biology

Study of basic relationships between the environment and humans. Discussion of constraints and relationships in nature from points of view of the physical and life sciences and investigation of how people make decisions to utilize the environment as a resource from the viewpoint of the social sciences. Attempts to link natural and social sciences for awareness of multifaceted nature of environmental problems.

3

BIOL 131 Principles of Biology I

The course will introduce first semester life science majors to the main themes used to study biology. Three main themes that extend throughout the curriculum include a detailed investigation of the scientific method, evolutionary theory and the diversity of life. The course will also examine the concepts of ecology and nutrient cycles.

3

BIOL 132 Principles of Biology I Laboratory

Principles of Biology I laboratory is designed to complement the Principles of Biology I lecture course. The lab exercises are designed to expose students to the main themes that are discussed in the lecture portion of the course: the scientific method and the diversity of life.

1

BIOL 133 Principles of Biology II

The course will provide an introduction to cell biology. Students are expected to learn the basic concepts of cellular chemistry, types of cells, cell division, and the central dogma of molecular biology. Students should also learn how cell biology is related to the fields of biochemistry, genetics, and molecular biology.

3

BIOL 134 Principles of Biology II Laboratory

The laboratory section for the lecture course. The experiments are designed to introduce students to techniques and procedures for studying cells. Students will perform basic skills and techniques that lead to proficiency for more advanced techniques in later courses. Emphasis is placed on students actually doing the procedures and performing the tasks to generate results.

1

BIOL 237 Genetics

The principles of genetic analysis and the nature of the gene. The course will cover Mendelian and molecular genetics. Key concepts covered will include the chromosomal and molecular basis of inheritance and replication, mutation and expression of genetic information.

3

Prerequisites

BIOL 133

BIOL 238 Genetics Laboratory

Exercises will focus on the analysis of the inheritance of genes. DNA isolation and manipulation experiments will be performed. Students will perform experiments in classical and molecular genetics.

1

Prerequisites

BIOL 133

Corequisites

BIOL 237

BIOL 243 Biodiversity

The goal of the course is to develop an expanded knowledge of evolution illustrated through a discussion of biodiversity. Course content deals with organic evolution, Mendelian and population genetics, evolutionary mechanisms, and taxonomy. The course will also provide a survey of life: viruses, bacteria, archaea, protists, fungi, plants, and animals as well as comparative anatomies and physiologies explained within an evolutionary context.

3

Prerequisites

BIOL 131

BIOL 244 Biodiversity Laboratory

Laboratory course emphasizing a survey of the diversity of life including protists, plants, and animals. Further development of knowledge regarding hypothesis testing, evolution, use of taxonomic keys and constructing phylogenies.

1

Prerequisites

BIOL 131

Corequisites

BIOL 243

BIOL 245 Human Anatomy and Physiology I

The first course in a two-course sequence. Examines the structural and functional characteristics of the human body. From discussions of concepts of physiological control and levels of organization, this course concentrates on the components of the musculoskeletal system, the integument and an extensive description and analysis of neural and endocrine systems of control. Lab exercises support lecture topics, and involve hands-on activities including dissection and physiological measurement. This course is designed for medical technology majors and those students planning careers in postgraduate allied health careers (e.g. pharmacy, physician's assistant, physical therapy).

4

Prerequisites

CHEM 116 and BIOL 133 and BIOL 134 and CHEM 125 and CHEM 126

BIOL 246 Human Anatomy and Physiology II

The second course in a two-course sequence, the first being BIOL 245 Human Anatomy & Physiology I. Concentrates on discussions of the structural and functional characteristics of the major organ systems of the body, including cardiovascular, respiratory, digestive, urinary and reproductive. Emphasis on the integrative nature of these systems to the maintenance of physiological function. Lab exercises support lecture topics, and involve hands-on activities including dissection and physiological measurement.

4

Prerequisites

BIOL 245

BIOL 250 Basic Concepts in Biology

Examination of selected areas of general biology for interested lower division major or non-major. Emphasis on developing basic background in such areas as botany, zoology, and the relationships between these fields and human society. Examples of courses offered include Field Natural History and Fungal Pathogens. Course may not be used as Biology major elective. Topics are determined by student interests.

1-6

Prerequisites

BIOL 111 or BIOL 131

BIOL 251 Basic Concepts in Biology

Examination of selected areas of general biology for interested lower division major or non-major. Emphasis on developing basic background in such areas as botany, zoology, and the relationships between these fields and human society. Examples of courses offered include Field Natural History and Fungal Pathogens. Course may not be used as Biology major elective. Topics are determined by student interests.

1-3

Prerequisites

BIOL 111 or BIOL 131

BIOL 256 Introduction to Clinical Science

A course designed to acquaint sophomores with various career opportunities available in medical technology. Educational requirements and professional responsibilities are also discussed. Small group discussions of clinical literature, and a tour of a hospital lab are featured.

1

BIOL 275 Health Professions Careers

The course is designed to assist students in learning the requirements for admission into health professional schools. We will review the admissions requirements for medical, dental, optometry and veterinary medical colleges and discuss how students can best develop a competitive admissions application. We will also discuss the history of the different health professions.

1

BIOL 296 Ecology of National Parks

This course will utilize a national park and the surrounding ecosystem as a case study to explore the science of ecology and ecosystem biology. The course will address the methods scientists use to explore natural systems. The course will also engage students in the use of basic research techniques and data analysis. We will emphasize ecological issues that have meaning for the management of public lands and thus address the application of scientific models outside of the discipline.

3

Corequisites

ENGL 296

BIOL 310 The Human Genome

The course will focus on human genes, their inheritance and the Human Genome Project. The broad subject area of genetics will be covered including studies of genes and genomes in other species to facilitate a better understanding of human genetics. For non-majors only.

3

Prerequisites

BIOL 110 or BIOL 111

BIOL 330 General Ecology

Introduction to ecology emphasizing general principles at individual, population, and community levels. Examples of various approaches (observation and experimentation, field and laboratory studies, and modeling and computer simulations) are considered.

3

Prerequisites

BIOL 243 or BIOL 144

BIOL 331 General Ecology Laboratory

Laboratories designed to give a diversity of experience, building upon principles of individual, population, and community ecology. A quantitative approach to the study of ecology is emphasized. Labs include plant and animal studies and field and laboratory experiments, as well as long- and short-term studies.

1

BIOL 333 Biochemistry

The structure and function of proteins and the regulation of metabolic pathways will be the central concepts presented in the course. Students should gain an understanding of the fundamental principles of the biology of protein molecules.

3

Prerequisites

CHEM 215 and (CHEM 225 or CHEM 230)

BIOL 334 Biochemistry Laboratory

Introduction to laboratory practice using biochemical techniques to isolate and characterize proteins. Enzyme kinetics and bioinformatics are also covered.

1

Prerequisites

BIOL 333*

BIOL 336 Mammalian Physiology

An integrative approach to systems physiology. After an initial discussion on mechanisms of cellular regulation of homeostasis, individual physiological systems, e.g. respiratory, cardiovascular, are examined. Organ and system action are related to demonstrate integration of function within the body. Major emphasis will be on normal human functions.

3

Prerequisites

BIOL 133 and CHEM 215

BIOL 337 Mammalian Physiology Lab

A laboratory course designed to complement BIOL 336 Mammalian Physiology. Laboratory exercises examine, through experimentation, the integrative functions of organs and systems within the body. Labs include excitable cell physiology, cardiovascular, excretory and exercise physiology. Wherever possible, human models are utilized.

1

Corequisites

BIOL 336

BIOL 338 Microbiology

The course includes a basic study of microbial taxonomy, morphology, biochemistry, and reproduction. Great emphasis is placed on medical microbiology, infectious diseases, microbial genetic regulation, and the application of microorganisms in recombinant gene technology. Laboratory includes identification of microbes by colonial and microscopic features, biochemical properties, and antibiotic sensitivities. Two lectures, one laboratory.

3

Prerequisites

BIOL 333 and (BIOL 237 or BIOL 335)

BIOL 340 Cell and Subcellular Biology

Cell structure and function at cellular and molecular level using animal, plant, and microbial cells to illustrate common and divergent tenets. Physical and chemical organization of cells, analysis of the cell concept, emphasis on biochemical, physiological, and ultrastructural properties. Laboratory exercises dealing with isolation and characterization of cell fractions. Two lectures, one laboratory.

3

Prerequisites

BIOL 333

BIOL 343 Conservation

Study of relationships of people with nature; extensive treatment of world and national problems related to use of natural resources. Basic approach is ecological, but impact of economic, sociological, political, and ethical concepts on human ecology examined. Note: Students in any Biology degree program may earn elective credit for only one of BIOL 343, 345 or 360.

3

Prerequisites

BIOL 111

BIOL 344 Parasitology

A survey of the more important protozoan and helminth parasites of humans. Special emphasis is given to epidemiology, pathogenesis, diagnosis, and treatment of common parasitic diseases.

1

Prerequisites

BIOL 131 and BIOL 133

BIOL 345 Emerging Infectious Diseases

The course will examine infectious diseases whose incidence in humans has increased within the past two decades. The course will focus on the etiological agents, infectious disease process, epidemiology, and the factors associated with the emergence and reemergence of these infectious diseases.

3

BIOL 360 AIDS and STDs

Discussion of the many ways AIDS and STDs (sexually transmitted diseases) have affected people and the societies in which they live. The course includes information about human physiology, immune defense mechanisms, and microbiology. Detailed biological discussions focus on the transmission of AIDS and STDs, disease symptoms, treatment, and prevention, as well as information on the historical accounts, global and regional impact, ethical, legal and public policy considerations, economic impact of AIDS and STDs, and the psychosocial impact on the individual, family and community. For non-majors only.

3

Prerequisites

BIOL 111 or BIOL 131 or BIOL 110

BIOL 365 Bioethics and New Embryology

Technological advancements such as in vitro fertilization (IVF), genetic engineering, and stem cell research have opened the door to many healthy debates about technological capabilities and the development of the embryo. To make informed judgments and participate effectively in debating these issues people should understand the science behind the ethical debates. The course is not about deciding what is right or wrong, but to provide a scientific basis for informed discussion.

3

Prerequisites

BIOL 110 or BIOL 111 or BIOL 133

BIOL 375 Genes, Health, and Society

The genetic makeup and environment in which humans develop makes each person unique. How do variations in these factors contribute to our physical and mental health? From a historical perspective, students will discuss how scientists and physicians study genes and genomes as well as how society reacts to the hope, hype, and fear surrounding these breakthroughs.

3

Prerequisites

BIOL 110 or BIOL 111 or BIOL 133

BIOL 397 Biochemistry Seminar I

Current biochemical research papers are analyzed in a journal club (open discussion) format. This course will help students to develop critical reading skills and underscore how an array of biochemical techniques are applied to address a research problem. Faculty from both biology and chemistry participate in this seminar.

1

Cross Listed Courses

CHEM 397

BIOL 410 Tropical Biology

A lecture and field course on the natural history and ecology of the neotropics. Students examine several terrestrial and marine tropical ecosystems, including lowland rain forests, elfin forests, mangrove communities, and coral reefs. Each student completes a field project and journal. One lecture per week during the semester followed by a two-week field experience in Costa Rica during winter break. Students are responsible for travel expenses. Restricted to majors with junior or senior standing.

3

BIOL 412 Sociobiology

The course covers social behavior from the perspective of evolutionary theory. Topics include sex, aggression, altruism, parent-offspring conflict, and the origin of cooperative societies.

3

Prerequisites

BIOL 330

BIOL 417 Comparative Animal Physiology

How animals maintain homeostasis in a non-homeostatic world. After a general introduction to mechanisms of cellular regulation and energetics the class will discuss specific physiological systems (respiratory, cardiovascular, osmoregulatory, etc.) and compare the modes and strategies employed by different animal groups in responding to changes in external environment. Particular attention directed to adaptations to marginal habitats, e.g. marine intertidal, deep sea hydrothermal vents, hot desert.

3

Prerequisites

BIOL 336

BIOL 419 Genes and Genomes

The course will focus on the study of DNA and genes from the paper by Watson and Crick to the Human Genome Project. The genetic and molecular approaches used to identify genes and the impact of genome study on society and current scientific research will be discussed.

3

Prerequisites

BIOL 237 or BIOL 335

BIOL 420 Population/Community Ecology

Reading and discussion of primary literature relating to population and community ecology. Topics include population growth, life history patterns, competition, plant-animal interactions, and community organization.

3

Prerequisites

BIOL 330

BIOL 421 Biological Conservation

An examination of species diversity with an emphasis on human activities which affect these patterns. Major topics will include the effects of land use practices, habitat fragmentation, invasive species and pollution on the current distribution and extinction patterns of plants and animals.

3

Prerequisites

BIOL 330

BIOL 422 Physiological Ecology

Reading and discussion of primary literature relating to animal interactions with the environment. Examination of potential effects of specific habitats (e.g. deserts, deep sea) and the physiological responses of various animals to these environmental challenges.

3

Prerequisites

BIOL 330

BIOL 424 Aquatic Biology

Classification and biology of major groups of organisms that inhabit freshwater environments, characteristics of aquatic habitats, pollution of aquatic environments, and the role of physical and chemical factors in aquatic ecosystems.

3

Prerequisites

BIOL 243

BIOL 426 Current Environmental Topics

The focus of the course is on global environmental issues. The issues examined have been making the news during the last year and at the time the course is taught. Changes in climate, overpopulation, pollution, conservation, development, genetically modified organisms, invasive species, illegal species trade, etc. are some of the ongoing issues that are covered in the course. The format of the course invites participation, discussion and critical thinking.

3

Prerequisites

BIOL 330

BIOL 427 Fisheries Science

The course is an overview of ichthyology, fisheries biology, and fisheries conservation. Students will be introduced to the taxonomic diversity of fish, fish adaptations, techniques and models used in the study of fish populations, community interactions, and issues concerning fisheries conservation and management. Special emphasis will be placed on understanding Great Lakes fisheries.

3

Prerequisites

BIOL 330

BIOL 429 Field Biology

A field-oriented course with emphasis on developing and testing scientific hypotheses. Activities include identification of local flora and fauna, using a wide variety of field techniques, statistical analysis, and writing scientific reports. Some Saturday field trips required.

3

Prerequisites

BIOL 330

BIOL 431 Senior Seminar

Reading, discussion, and analysis of current topics of biological significance using original source material from primary biological periodicals. Students prepare and present a seminar based on an extensive review of the available literature.

1

BIOL 434 Animal Behavior

The course will provide background to the discipline of animal behavior and examine the levels of questioning in this field. It will discuss the influence of genetics and the environment on behavior (nature vs. nurture). It will then magnify our focus to the roots of behavior, the proximate causes of behavior, specifically its neural and hormonal control. It will examine the cases of bird song, electric fish EODs, shark electroreception, moth hearing and bat echolocation. It will then focus on those behaviors that make up the many tasks animals must accomplish to survive and reproduce.

3

Prerequisites

BIOL 243 or BIOL 144

BIOL 435 Developmental Biology

A study of animal development integrating descriptive, experimental, cellular, and molecular studies of gametogenesis, fertilization, cleavage, gastrulation, induction, and maturation. Labs examine development from an historical perspective including: descriptive, experimental and molecular embryology incorporating hypothesis testing through the use of micromanipulation, cell culture and immunohistochemistry. Two lectures, one laboratory.

3

Prerequisites

BIOL 333

BIOL 436 Molecular Biology

Students will study the basic principles of molecular biology including DNA replication, transcription, and translation. Specific attention will be given to the molecular interactions between protein, DNA, and RNA molecules. Students should gain an understanding of the role of molecular interactions in the basic processes required for the flow of information in cells.

3

Prerequisites

BIOL 237 or BIOL 333 or BIOL 335

BIOL 437 Molecular Genetics Laboratory

Molecular genetics is a broad term that describes a collection of techniques that biologists use to study and manipulate the physiology, biochemistry, and genetics of a cell at a molecular level. This course is designed to help students build their molecular ?Ç£toolkit?Ç¥ and teach them how to bring the concepts learned in lecture courses to bear on a research project.

2

Prerequisites

BIOL 237 and BIOL 238 and BIOL 333 or CHEM 333 and BIOL 334 or CHEM 334

BIOL 438 Molecules and Medicine

The course will cover material on traditional drugs used in medicine and discuss the transition to new drugs that have been designed to interact with a specific target. An emphasis will be on understanding the molecular details of drug-target interactions and the mechanism of actions of pharmaceutical drugs. Students will discuss ethical issues relating to medicine and pharmaceuticals. Students will read primary literature and review articles as the primary sources of information in the course.

3

Prerequisites

BIOL 333

BIOL 440 Undergraduate Research

Independent study and research of mutual interest with faculty member in such areas as morphology, physiology, evolution, development, population dynamics, genetics, biochemistry, cell and subcellular biology, microbiology, ecology, behavior and conservation. Course may be repeated; maximum of 12 credits count toward the B.S. degree, only 3 of which may be included in a Biology major. Note: Students may earn Biology elective credit for only one of BIOL 440/1 or 458. Permission of department required.

1-3

BIOL 441 Undergraduate Research

Independent study and research of mutual interest with faculty member in such areas as morphology, physiology, evolution, development, population dynamics, genetics, biochemistry, cell and subcellular biology, microbiology, ecology, behavior and conservation. Course may be repeated; maximum of 12 credits count toward the B.S. degree, only 3 of which may be included in a Biology major. Note: Students may earn Biology elective credit for only one of BIOL 440/1 or 458. Permission of department required.

1-3

BIOL 443 Plant Physiology

Study of the life processes and responses of plants, including water relations and transport, photosynthesis and general metabolism, mineral and organic nutrition, photoperiodic responses and rhythms, growth and differentiation, and plant relationships with the environment.

3

Prerequisites

BIOL 133

BIOL 447 Evolution

Consideration of the theoretical framework of evolutionary biology and the mechanisms of evolution. Special topics include microevolution, macroevolution, and coevolution.

3

Prerequisites

BIOL 237 or BIOL 243 or BIOL 335

BIOL 450 Modern Concepts in Biology

An in-depth examination of selected areas of biology for interested upper-division students. Topics are determined by faculty and student interests and emphasize methods and recent research developments. Examples of topics currently offered on a rotating basis include: Biomembranes, Hormone Mechanisms, Molecular Biology, Cell/Hybridoma Culture, and Biology of Terrestrial Vertebrates.

1-3

BIOL 451 Modern Concepts in Biology

An in-depth examination of selected areas of biology for interested upper-division students. Topics are determined by faculty and student interests and emphasize methods and recent research developments. Examples of topics currently offered on a rotating basis include: Biomembranes, Hormone Mechanisms, Molecular Biology, Cell/Hybridoma Culture, and Biology of Terrestrial Vertebrates.

1-3

BIOL 453 Basic Hematology

Introduction to the study of blood, its cellular components, and various blood diseases. Laboratory exercises include a variety of manual techniques involved with blood cell counts and determinations.

1

Prerequisites

BIOL 131 and BIOL 133

BIOL 457 Biostatistics

A review of statistical tests frequently used in the biological sciences. Emphasis is placed on understanding experimental design and what statistics can and cannot do. Uses of computer statistical packages are also considered.

3

Prerequisites

STAT 250

BIOL 458 Lab Supervision in Biology

A supervisory experience in teaching of the biology department's laboratories under the guidance of a faculty member. Student experiences may include; preparing materials for the lab, and demonstrating procedures and techniques to students. Note: Students may earn Biology elective credit for only one of BIOL 440/1 or 458. Permission of department required.

1

BIOL 461 Immunology and Serology

Study of the mechanisms of the immune response including cellular basis of immunity and molecular basis of antigen-antibody reactions. Regulation of antibody production and cell-mediated reactivity examined. Current clinical applicability considered in discussion of tumor, transplantation, allergy-related, and autoimmune immunobiology. Several laboratory exercises included involving serological/immunological determinations detecting antigen-antibody interactions. Three lectures.

3

Prerequisites

BIOL 333 and (BIOL 237 or BIOL 335)

BIOL 465 Advanced Experimental Biochemistry

State-of-the-art biochemical and molecular techniques are taught within this hands-on, laboratory-based course. Potential topics include the polymerase chain reaction (PCR), oligonucleotide synthesis, DNA/protein sequencing and analysis (BLAST, DNASIS), pulse-field gel electrophoresis, gas chromatography-mass spectroscopy (GC-MS), nuclear magnetic resonance (NMR) spectroscopy, high performance liquid chronatography (HPLC), immunochemistry, and/or other contemporary techniques.

2

Prerequisites

BIOL 334

Cross Listed Courses

CHEM 465

BIOL 466 Current Issues in Developmental Biology

Course focuses on recent developments in the rapidly expanding field of developmental biology. With the advent of the tools available to molecular biologists, the course will study recent advances in the genetic understanding of various aspects of embryological development and regeneration. The course will present a variety of topics including: fertilization, gastrulation, maternal effect genes, pattern formation, and evolutionary aspects of development. Junior standing in major required.

3

BIOL 468 Biomembranes

The objectives of the course include: identification of different types of membranes based upon composition, morphology and cellular functions, and examination of experiments which have provided understanding of how membranes function in cells and organisms. Topics include membrane composition, electron microscope techniques, membrane transport, membrane proteins and enzymes, receptors, hormone interaction, cell recognition, secretion, and biogenesis of membranes.

3

Prerequisites

BIOL 333

BIOL 469 Eukaryotic Gene Regulation

In-depth examination of the ways in which eukaryotic cells regulate their protein composition at the levels of genome replication, transcription, post-transcriptional modifications, and translations. Topics include chromatin structure, transcription factors, and DNA sequence elements, several cell-type specific transcriptional events and how they are regulated, as well as how transcriptional regulation gone awry can cause cancer.

3

Prerequisites

BIOL 237 or BIOL 335

BIOL 470 Hormone Mechanisms

Course will examine the basic physiological, cellular and molecular pathways which regulate metabolism, growth, and neurological activities of organisms, especially mammals. Discussions will follow text information and general models will be supported with primary research literature to show developments from recent experiments.

3

Prerequisites

BIOL 333

BIOL 472 Microbial Pathogenesis

Course focuses on the molecular basis of microbial pathogenesis. Through the application of molecular techniques to the study of the microbe-host interaction, scientists are gaining a fundamental understanding of the virulence mechanisms of microbial pathogens. Using primary literature the course will illustrate how the integration of the molecular basis of virulence mechanisms with the clinical aspects of disease has enhanced understanding of the pathogenesis of infectious diseases.

3

BIOL 473 Animal Communication

The course will provide a background for the field of animal communication including a discussion of definitions of animal communication. It will then survey the production, transmission and reception of auditory, visual, and chemical signals. Optimality theory and signal detection theory will be introduced as they apply to animal communication. It will spend some time on how signals come to be and why they have the design they do (signal evolution). Finally, it will investigate signaling in a variety of situations such as between potential mates, other conspecifics, as well as environmental and autocommunication signaling.

3

Prerequisites

BIOL 330

BIOL 475 Advanced Biochemistry

A continuation of BIOL 333, the course explores biochemical concepts and pathways with an emphasis on problem solving. Cellular control and coordination of biochemical pathways is emphasized in light of an advanced understanding of protein biochemistry. Lecture only.

3

Prerequisites

BIOL 333

Cross Listed Courses

CHEM 475

BIOL 480 Molecular Biology of Disease

The course will cover topics relating to the genetic and biochemical etiology of human disease. Through examination of the primary literature, students will become familiar with the techniques used to study and treat diseases at the molecular level. Specific topics covered include inborn errors in metabolism, cholesterol homeostasis, protein folding diseases, cancer, gene therapy, and stem cell therapy. Students will formulate an independent research proposal based on examination of current literature on a disease of their choosing.

3

Prerequisites

BIOL 333

BIOL 490 Biology Internship

Approved biology-related experiences in academia, government, industry or other foundations. Requires the permission of the department and faculty sponsor.

1-15

BIOL 497 Biochemistry Seminar II

Students prepare oral presentations based on an assessment of current biochemical research papers. The course will help students to further develop critical reading and scientific communication skills. Faculty from both biology and chemistry participate in the seminar.

1

Prerequisites

BIOL 397

Cross Listed Courses

CHEM 497

BIOL 499 Independent Study - Undergraduate

In Independent Study, students will perform literature reviews and learn how to design experiments and collect and analyze data. Student expectations will vary based upon the biological discipline and the number of credits. Junior/Senior standing in the major.

1-3

BIOL 440-441 Undergraduate Research

Independent study and research of mutual interest with faculty member in such areas as morphology, physiology, evolution, development, population dynamics, genetics, biochemistry, cell and subcellular biology, microbiology, ecology, behavior and conservation. Course may be repeated; maximum of 12 credits count toward the B.S. degree, only 3 of which may be included in a Biology major. Note: Students may earn Biology elective credit for only one of BIOL 440/1 or 458. Permission of department required.

1-3

BIOL 450-451 Modern Concepts in Biology

An in-depth examination of selected areas of biology for interested upper-division students. Topics are determined by faculty and student interests and emphasize methods and recent research developments. Examples of topics currently offered on a rotating basis include: Biomembranes, Hormone Mechanisms, Molecular Biology, Cell/Hybridoma Culture, and Biology of Terrestrial Vertebrates.

1-3

BIOL 501 Biochemistry

Advanced discussion of biological chemistry; chemistry of carbohydrates, lipids and proteins, and nucleic acids; bioenergetics; the structure and mechanism of enzyme action; protein biosynthesis; molecular genetics; selected topics in immunochemistry, and biochemical endocrinology.

3

Prerequisites

CHEM 216

BIOL 502 Methods in Biochemistry

Theory and laboratory experiments demonstrating the techniques and applications of contemporary biochemistry including electrophoresis, chromatography, centrifugation, radioisotope methods, DNA sequencing, enzymology, spectrophotometry and gas chromatography.

3

Prerequisites

BIOL 501

BIOL 510 Tropical Biology

A lecture and field course on the natural history and ecology of the neotropics. Students examine several terrestrial and marine tropical ecosystems, including lowland rain forests, elfin forests, mangrove communities, and coral reefs. Each student completes a field project and journal. One lecture per week during the semester followed by a two-week field experience in Costa Rica during winter break. Students are responsible for travel expenses.

3

BIOL 512 Sociobiology

The course covers social behavior from the perspective of evolutionary theory. Topics include sex, aggression, altruism, parent-offspring conflict, and the origin of cooperative societies. Graduate students will write a research intensive review article, using primary literature. Papers should provide a thorough review of a specific sociobiological hypothesis applied to limited taxa. I expect you to cover all up-to-date primary sources that pertain to your topic. The paper should be about 10 pages long. Topics must be approved by the instructor. Graduate students will present their term papers to the class during the final two class periods. Presentations should use PowerPoint and last 15 minutes plus 3-5 minutes for questions.

3

BIOL 517 Comparative Animal Physiology

How animals maintain homeostasis in a non-homeostatic world. After a general introduction to mechanisms of cellular regulation and energetics, discussion will include specific physiological systems (respiratory, cardiovascular, osmoregulatory, etc.) and compare the modes and strategies employed by different animal groups in responding to changes in external environment. Particular attention directed to adaptations to marginal habitats, e.g. marine intertidal, deep sea hydrothermal vents, hot desert.

3

Prerequisites

BIOL 336

BIOL 519 Genes and Genomes

The course will focus on the study of DNA and genes from the paper by Watson and Crick to the Human Genome Project. The genetic and molecular approaches used to identify genes and the impact of genome study on society and current scientific research will be discussed.

3

BIOL 520 Population and Community Ecology

Reading and discussion of primary literature relating to population and community ecology. Topics include population growth life history patterns, competition, plant-animal interactions, and community organization.

3

Prerequisites

BIOL 330

BIOL 522 Physiological Ecology

Reading and discussion of primary literature relating to physiological and ecosystem ecology. Topics include resource acquisition, energetics, nutrient cycling, and energy flow.

3

Prerequisites

BIOL 330

BIOL 524 Aquatic Biology

The course covers the classification and biology of major groups of organisms found in fresh water, characteristics of aquatic habitats, pollution of aquatic environments, and the role of physical and chemical factors in aquatic ecosystems.

3

Prerequisites

BIOL 330

BIOL 526 Current Environmental Topics

The focus of the course is on global environmental issues. The issues examined have been making the news during the last year and at the time the course is taught. Changes in climate, overpopulation, pollution, conservation, development, genetically modified organisms, invasive species, illegal species trade, etc. are some of the ongoing issues that are covered in the course. The format of the course invites participation, discussion and critical thinking.

3

BIOL 527 Fisheries Science

The course is an overview of ichthyology, fisheries biology, and fisheries conservation. Students will be introduced to the taxonomic diversity of fish, fish adaptations, techniques and models used in the study of fish populations, community interactions, and issues concerning fisheries conservation and management. Special emphasis will be placed on understanding the Great Lakes fisheries.

3

Prerequisites

BIOL 144

BIOL 534 Animal Behavior

The course will first provide background to the discipline of animal behavior and examine the levels of questioning in this field. The class will discuss the influence of genetics and the environment on behavior (nature vs. nurture). It will magnify its focus to the roots of behavior, the proximate causes of behavior, specifically its neural and hormonal control. The class will examine the cases of bird song, electric fish EODs, shark electroreception, moth hearing and bat echolocation, and then focus on those behaviors that make up the many tasks animals must accomplish to survive and reproduce.

3

BIOL 538 Molecules and Medicine

The course will cover material on traditional drugs used in medicine and discuss the transition to new drugs that have been designed to interact with a specific target. An emphasis will be on understanding the molecular details of drug-target interactions and the mechanism of actions of pharmaceutical drugs. Students will discuss ethical issues relating to medicine and pharmaceuticals. Students will read primary literature and review articles as the primary sources of information in the course.

3

Prerequisites

BIOL 501

BIOL 543 Plant Physiology

Study of the life processes and responses of plants, including water relations and transport, photosynthesis and general metabolism, mineral and organic nutrition, photoperiodic responses and rhythms, growth and differentiation, and plant relationships with the environment. Laboratory includes problems and exercises in whole plant physiology as well as at the molecular level. The laboratory stresses methods rather than results. Two lectures, one laboratory.

3

BIOL 544 Radiation Biology

Lectures on techniques required for application of radioactive isotopes to biological research. Experimental isotope tracer techniques deal with in vitro and in vivo labeling as well as autoradiographic studies. Variety of living systems used.

3

BIOL 547 Evolution

Consideration of the theoretical framework of evolutionary biology and the mechanisms of evolution. Special topics include microevolution, macroevolution and coevolution.

3

BIOL 557 Biostatistics

Statistical tests frequently used in the biological sciences. Emphasis is placed on understanding what statistics can and cannot do, the meaning of a statistical test, and how to choose an appropriate statistical test. Uses of micro-computer and mainframe statistical packages (SPSS or MINITAB) are also considered.

3

BIOL 564 Mammalogy

Consideration of taxonomy, ecology, and physiology of mammals; world fauna examined although emphasis on local species. Field population studies, collection and preservation of specimens, and studies in physiological adaptations of mammals.

3

BIOL 566 Current Issues in Developmental Biology

Course focuses on recent developments in the rapidly expanding field of developmental biology. With the advent of the tools available to molecular biologists, the course will study recent advances in the genetic understanding of various aspects of embryological development and regeneration. The course will present a variety of topics including: fertilization, gastrulation, maternal effect genes, pattern formation, and evolutionary aspects of development.

3

BIOL 567 Biomembranes

The objectives of this course include: identification of different types of membranes based upon composition, morphology and cellular functions, and examination of experiments which have provided understanding of how membranes function in cells and organisms. Topics include membrane composition, electron microscope techniques, membrane transport, membrane proteins and enzymes, receptors, hormone interaction, cell recognition, secretion, and biogenesis of membranes.

3

Prerequisites

BIOL 333

BIOL 569 Eukaryotic Gene Regulation

In-depth examination of the ways in which eukaryotic cells regulate their protein composition at the levels of genome replication, transcription, post-transcriptional modifications, and translation. Topics include chromatin structure, transcription factors, and DNA sequence elements, several cell-type specific transcriptional events and how they are regulated, as well as how transcriptional regulation gone awry can cause cancer.

3

Prerequisites

BIOL 241 and BIOL 335

BIOL 570 Hormone Mechanisms

The course will examine the basic physiological, cellular and molecular pathways which regulate metabolism, growth, and neurological activities of organisms, especially mammals. Discussions will follow text information and general models will be supported with primary research literature to show developments from recent experiments.

3

Prerequisites

BIOL 333

BIOL 572 Microbial Pathogenesis

The course focuses on the molecular basis of microbial pathogenesis. Through the application of molecular techniques to the study of the microbe-host interaction, scientists are gaining a fundamental understanding of the virulence mechanisms of microbial pathogens. Using primary literature the course will illustrate how the integration of the molecular basis of virulence mechanisms with the clinical aspects of disease has enhanced understanding of the pathogenesis of infectious diseases.

3

Prerequisites

BIOL 333 and BIOL 335

BIOL 573 Animal Communication

The course will first provide a background for the field of animal communication including a discussion of definitions of animal communication. The class will then survey the production, transmission and reception of auditory, visual, and chemical signals. Optimality theory and signal detection theory will be introduced as they apply to animal communication. The class will spend some time on how signals come to be and why they have the design they do (signal evolution), and will investigate signaling in a variety of situations such as between potential mates, other conspecifics, and autocommunication signaling.

3

BIOL 580 Molecular Biology of Disease

The course will cover topics relating to the genetic and biochemical etiology of human disease. Through examination of the primary literature, students will become familiar with the techniques used to study and treat diseases at the molecular level. Specific topics covered include inborn errors in metabolism, cholesterol homeostasis, protein folding diseases, cancer, gene therapy, and stem cell therapy. Students will formulate an independent research proposal based on examination of current literature on a disease of their choosing.

3

BIOL 550-551 Current Concepts in Biology

An in-depth examination of selected areas of biology for interested upper-division students. Topics are determined by faculty and student interests and emphasize methods and recent research developments. Examples of topics currently offered on a rotating basis include: Biomembranes, Molecular Genetics, Cell and Hybridoma Culture, Enzymes, Ethology, Hormone Mechanisms, Bioenergetics, Microbial Genetics, Field Biology, and Advanced Developmental Biology, PCR, DNA Synthesis and Immunology.

1-3

BIOL 600 Seminar

Presentation of detailed study of topic of current interest in the biological literature. Attendance and one seminar presentation required for three semesters of all candidates for the master's degree. Students completing thesis research must present their results orally prior to their scheduled thesis defense.

1-3

BIOL 601 Seminar

Presentation of detailed study of topic of current interest in the biological literature. Attendance and one seminar presentation required for three semester of all candidates for the master's degree. Students completing thesis research must present their results orally prior to their scheduled thesis defense.

1

BIOL 611 Cell Regulation

Integrated study of regulation at various levels within the cell. Molecular control of cellular activity and its interconnection with biochemistry including regulation of enzyme activity, nucleic acid and protein biosynthesis, metabolic control by hormones, and membrane regulatory functions.

3

Prerequisites

BIOL 501

BIOL 646 Reproductive Physiology

Treatment of reproductive mechanisms in higher vertebrates; particular attention to mammals. Topics include biology of sex, structure-function relationship in male and female reproductive systems, gametogenesis, gonadal steroids, nongonadal endocrine control mechanisms, cyclic reproductive phenomena, insemination and fertilization, viparity, pregnancy, parturition and lactation, fertility and sterility, and effects of environment and nutrition on reproductive processes.

3

Prerequisites

BIOL 501

BIOL 650 Special Topics in Biology

Comprehensive reviews of current state of biological investigation for advanced graduate students. Analysis of frontiers of scientific advancement in molecular biology, quantitative ecology, and physiology.

1-3

BIOL 690 Thesis Research

Directed research culminating in the preparation of a thesis.

1-9

BIOL 691 Thesis

Directed research culminating in the preparation of a thesis.

1-9

BIOL 699 Independent Study - Graduate

Primarily intended for thesis graduate students wishing to perform a thorough and directed literature review in support of their graduate research. Graduate students will develop the independent study activities with the assistance and approval of their research professor; formal assessment mechanisms to be determined by the professor. May be appropriate for non-thesis graduate students wishing to perform a thorough and directed literature review under the supervision of a professor, leading to the development of a formal paper.

1-3